The high mutation rate of SARS-CoV-2 genomic RNA has made COVID-19 more difficult to eradicate using currently available interventions.Hence, newer pharmaceutical strategies must be Acrylic Puzzle developed, especially those generally complementary and alternative medicines.In the current study, stem bark of Bridelia ferruginea Benth is presented a
A Nonlinear Mixed Effects Approach for Modeling the Cell-To-Cell Variability of Mig1 Dynamics in Yeast.
The last decade has seen a rapid development of experimental techniques that allow data collection from individual cells.These techniques have enabled the discovery and characterization of variability within a population of genetically identical cells.Nonlinear mixed effects (NLME) modeling is an established framework for studying variability betwe
F1-ECAC: Enhanced Evolutionary Clustering Using an Ensemble of Supervised Classifiers
Clustering is an unsupervised learning technique used in data mining for finding groups with increased object similarity within but not between them.However, the absence of a-priori knowledge on the optimal clustering criterion, and the strong bias of traditional algorithms towards clusters with a specific shape, size, or density, raise the need fo
Measuring and modeling the effects of vagus nerve stimulation on heart rate and laryngeal muscles
Abstract Background Reduced RANGEMASTER heart rate (HR) during vagus nerve stimulation (VNS) is associated with therapy for heart failure, but stimulation frequency and amplitude are limited by patient tolerance.An understanding of physiological responses to parameter adjustments would allow differential control of therapeutic and side effects.To i
Robust uncertainty quantification of the volume of tsunami ionospheric holes for the 2011 Tohoku-Oki earthquake: towards low-cost satellite-based tsunami warning systems
We develop a new method to analyze the total electron content RANGEMASTER (TEC) depression in the ionosphere after a tsunami occurrence.We employ Gaussian process regression to accurately estimate the TEC disturbance every 30 s using satellite observations from the global navigation satellite system (GNSS) network, even over regions without measure